The use of enamines in the synthesis of heterocycles
摘要：
The reaction of the enamine N -styryl pyrrolidine with 4,6-dichloro-5-nitropyrimidine and 4-amino-6-chloro-5-nitropyrimidine was investigated. Reduction of resultant compounds was followed by spontaneous ring closure to the pyrrolo[3,2- d ]pyrimidine ring system. This reaction sequence should provide a general method for the preparation of 4,7-disubstituted pyrrolo[3,2- d ]-pyrimidines.
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DOI：
10.1002/jhet.5570090521
被引量：
年份：
1972
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