Genetic variation for stress-response hormesis in C. elegans lifespan

阅读量:

38

作者:

M RodriguezLB SnoekJAG RiksenRP BeversJE Kammenga

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摘要:

Hormetic effects in lifespan have been reported using C. elegans mutants in one genotype N2. Yet, induced mutations do not yield insight regarding the natural genetic variation. We report genetic variation for stress-response hormesis in C. elegans lifespan. A QTL was detected on chromosome II explaining variation in hormesis. This QTL was confirmed by introgressing relatively small CB4856 regions into chromosome II of N2

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DOI:

10.1016/j.exger.2012.05.005

被引量:

70

年份:

2012

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