Resolution of Racemic Acids by Irreversible Lipase-Catalyzed Esterification in Organic Solvents

阅读量:

9

作者:

R MorroneM PiattelliG Nicolosi

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摘要:

The reversible nature of the direct esterification of acids with alcohols limits the use of this process in the biocatalytic kinetic resolution of chiral acids. A new irreversible procedure, using orthoesters, has been developed.

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DOI:

10.1002/1099-0690(200104)2001:8<1441::aid-ejoc1441>3.0.co;2-d

年份:

2001

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