Molecular interactions on microarrays.
摘要：
The structural features of nucleic acid probes tethered to a solid support and the molecular basis of their interaction with targets in solution have direct implication for the hybridization process. We discuss how arrays of oligonucleotides provide powerful tools to study the molecular basis of these interactions on a scale which is impossible using conventional analysis.
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关键词：
DNA Ligases DNA-Directed DNA Polymerase Oligonucleotide Probes Oligonucleotide Array Sequence Analysis Base Composition Binding Sites Base Sequence Nucleic Acid Conformation Base Pairing
DOI：
10.1038/4429
被引量：
年份：
1999
Nature
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掌桥科研
万方医学
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