Pivotal Roles of GM-CSF in Autoimmunity and Inflammation
摘要：
Granulocyte macrophage-colony stimulating factor (GM-CSF) is a hematopoietic growth factor, which stimulates the proliferation of granulocytes and macrophages from bone marrow precursor cells. In autoimmune and inflammatory diseases, Th17 cells have been considered as strong inducers of tissue inflammation. However, recent evidence indicates that GM-CSF has prominent proinflammatory functions and that this growth factor (not IL-17) is critical for the pathogenicity of CD4
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关键词：
GRANULOCYTE-macrophage colony-stimulating factor AUTOIMMUNITY HEMATOPOIETIC growth factors INFLAMMATION CELL proliferation MACROPHAGES
DOI：
10.1155/2015/568543
被引量：
年份：
2015
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