Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

来自 EBSCO

阅读量:

197

作者:

DC WileyIA WilsonJJ Skehel

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摘要:

Four 'antigenic sites' on the three-dimensional structure of the influenza haemagglutinin are identified. At least one amino acid substitution in each site seems to be required for the production of new epidemic strains between 1968 and 1975.

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DOI:

10.1038/289373a0

被引量:

4087

年份:

1981

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2010
被引量:228

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