摘要：

Sera from 308 patients, of whom 242 were suffering from various types of tumours and 66 from non-cancerous diseases, were tested for the presence of α1-globulin. The reaction was positive in 17 out of 28 patients with primary cancer of the liver. Among these there were 18 cases with tumours of the hepatocellular type, and 14 of these gave a positive α1-globulin reaction. The test was negative in 67 patiens with metastatic liver cancers. This confirms Tatarinov's (1964) findings indicating that α1-globulin is dectected in sera of patients with primary hepatocellular carcinoma. In addition, α1-globulin was found in some patients with mixed hepatocellular and cholangiocellular carcinoma. The fact that the α1-globulin is usually positive in hepatocellular and mixed liver carcinomas and negative in metastatic liver tumours makes it potentially useful for the diagnosis of liver tumours α1-Globulin was found also in the blood of patients with testicular teratoblastoma, which exhibited some elements of embryonal carcinoma. This novel finding cannot be interpreted as yet. The test was negative in other types of testicular tumours.

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