摘要：

Phenylethanolamino- and phenylethanolaminomethyltetralines of formula (I) ##STR1## wherein X represents a hydrogen atom, a halogen atom, a (C. sub.1 -C.sub.4)alkyl group or a trifluoromethyl group,< P>A represents a bond between the --COOR group and the tetraline ring, a (C. sub.1 -C.sub.4)alkylene or a (C.sub.2 -C.sub.4)alkenylene group,< P> R is hydrogen or a (C.sub.1 -C.sub.4)alkyl group, and< P> n is 0 or 1and their salts, are typically prepared by reaction of an epoxide of formula (IIa) ##STR2## with a tetraline derivative of formula (III) ##STR3## wherein A and n are as defined above and R' is a (C.sub.1 -C.sub.4)alkyl group, optionally followed by basic hydrolysis to obtain the compounds (I) wherein R is hydrogen. The new compounds show very interesting properties as antidepressant and intestinal spasmolytic agents.The new intermediates of formula (III) are also claimed.

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