Diphosphate salt of a 4" -substituted-9-deoxo-9A-AZA-9A-homoerythromycin derivative and its pharmaceutical composition
申请(专利)号：
10/218154
申请日期：
08/12/2002
公开/公告号：
US20030092642
公开/公告日期：
05/15/2003
摘要：
This invention relates to a novel crystalline diphosphate salt of (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-dideoxy-3-C-methyl-3-0-methyl-4-C-[(propylamino)methyl]-α-L-ribo-hexopryanosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one that is useful as an antibacterial and antiprotozoal agent in mammals. This invention also relates to pharmaceutical compositions containing the free base of the diphosphate salt and the methods of treating bacterial and protozoal infections in mammals by administering the free base of the diphosphate to mammals requiring such treatment. The free base of the diphosphate salt of the present invention possesses potent activity against various bacterial and protozoal infections when given by parenteral application to mammals.
展开
相似文献
参考文献
引证文献
站内活动
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
