Biodegradable, implantable drug delivery device, and process for preparing and using the same

阅读量:

37

申请(专利)号:

CA19740199552

申请日期:

0000-00-00

公开/公告号:

CA1045977A

公开/公告日期:

1979-01-09

申请(专利权)人:

ARTHUR D. LITTLE, INC.

发明人:

KR Sidman

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被引量:

492

摘要:

An implantable drug delivery device comprising a matrix formed of a poly-&agr;-amino acid component having one or more drugs and/or diagnostic agents physically contained therein. The drug or diagnostic agent is released through one or both of two mechanisms: diffusion and biodegration which results from the action of enzymes, present in the host in which the implant is placed, on the polymeric matrix material. The implant device may be designed to release the drug or drugs at predetermined rates and in predetermined sequence. One preferred configuration for the implant device is a rod which may be inserted with a trocar.

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1996
被引量:27

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0

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