Harnessing actin dynamics for clathrin-mediated endocytosis
摘要:
Actin polymerization often occurs at the plasma membrane to drive the protrusion of lamellipodia and filopodia at the leading edge of migrating cells. A role for actin polymerization in another cellular process that involves the reshaping of the plasma membrane--namely endocytosis--has recently been established. Live-cell imaging studies are shedding light on the order and timing of the molecular events and mechanisms of actin function during endocytosis.
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关键词:
ALDRICH-SYNDROME PROTEIN BINDING-PROTEIN COATED PITS N-WASP ARP2/3 COMPLEX BUDDING YEAST PLASMA-MEMBRANE IN-VIVO LIVING CELLS MYOSIN-I
DOI:
10.1038/nrm1940
被引量:
年份:
2006

















































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