Formulation for topical non-invasive application in vivo

阅读量:

19

申请(专利)号:

AU19990025137

申请日期:

1998-12-23

公开/公告号:

AU2513799A

公开/公告日期:

2000-07-31

申请(专利权)人:

IDEA INNOVATIVE DERMALE APPLIKATIONEN GMBH

发明人:

G Cevc

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被引量:

87

摘要:

A formulation comprising molecular arrangements capable of penetrating pores in a barrier, owing to penetrant adaptability, despite the fact that the average diameter of said pores is smaller than the average penetrant diameter, provided that the prenetrants can transport agents or else enable agent permeation through the pores after penetrants have entered pores, characterized in that the formulation comprises at least one consistency builder in an amount that increases the formulation to maximally 5 Nm/s so that spreading over, and retention at, the application area is enabled and/or at least one antioxidant in an amount that reduces the increase of oxidation index to less than 100% per 6 months and/or at least one microbiocide in an amount that reduces the bacterial count of 1 million germs added per g of total mass of the formulation to less than 100 in the case of aerobic bacteria, to less than 10 in the case of entero-bacteria, and to less than 1 in the case of or , after a period of 4 days.

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2010
被引量:14

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