Prevention of vertebrate neuronal death by the crmA gene
摘要：
Interleukin-1β converting enzyme (ICE) is a mammalian homolog of CED-3, a protein required for programmed cell death in the nematode Caenorhabditis elegans. The activity of ICE can be specifically inhibited by the product of crmA, a cytokine response modifier gene encoded by cowpox virus. Microinjection of the crmA gene into chicken dorsal root ganglion neurons was found to prevent cell death induced by deprivation of nerve growth factor. Thus, ICE is likely to participate in neuronal death in vertebrates.
展开
DOI：
10.1126/science.8303301
被引量：
年份：
1994
Wiley
Semantic Scholar
万方医学
Europe PMC
NCBI
查看更多
JSTOR
NCBI
JBC
AACR
dialnet.unirioja.es
adsabs.harvard.edu
ResearchGate
ResearchGate
(全网免费下载)
ProQuest
EBSCO
genetics.org
www.socolar.com
jneurosci.org
emboj.embopress.org
highbeam.com
plefa.com
deepdyve.com
scienceopen.com
digitalcommons.cedarville.edu
stroke.ahajournals.org
works.bepress.com
jcs.biologists.org
molpharm.aspetjournals.org
onAcademic
sciencemag.org
学术范
jvi.asm.org
jcb.rupress.org
yuan.med.harvard.edu
(全网免费下载)
mendeley.com
osti.gov
(全网免费下载)
学术范
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
请先登入
相似文献
参考文献
引证文献
来源期刊
引用走势
1997
被引量：228
辅助模式
0
引用
文献可以批量引用啦~
欢迎点我试用！
