Phenylethanolaminomethyltetraliner and the preparation thereof and to pharmaceutical compositions containing them
摘要：
New phenylethanolaminomethyltetralins of formula (I) <IMAGE> (I) wherein E represents hydrogen, (C1-C4)alkyl, (C1-C4)alkoxy, phenyl, nitro, halogen, or trifluoromethyl, L represents hydrogen, (C1-C4)alkyl, (C1-C4)alkyoxy, phenyl, nitro, or halogen, or E and L taken together represent a group -CH=CH-CH=CH- or -CH2-CH2-CH2-CH2-, and G represents hydrogen, chloro, hydroxy or an -OG' group wherein G' represents a (C1-C4(alkyl group either unsubstituted or substituted with hydroxy, (C1-C4)alkoxy, (C1-C4)alkoxycarbonyl, carboxy, or (C3-C7)cycloalkyl; a (C3-C7)cycloalkyl group; or a (C2-C4)alkanoyl group; and salts thereof, are described which showed to be active as intestinal motility modulating agents and intraocular hypertension lowering agents. Also described is a process for the preparation of the new compounds and the intermediates of formula (III) <IMAGE> (III) employed in said process.
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年份：
1990
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