Effect of a new hypoglycemic agent, A-4166 [(-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine], on postprandial blood glucose excursion: compari...

)-N-(trans-4-Isopropylcyclohexanecarbonyl)-D-phenylalanine (A-4166) is a new nonsulfonylurea hypoglycemic agent that lowers blood glucose by stimulating in...

T Ikenoue，K Okazaki，S Fujitani，... - 《Biological & Pharmaceutical Bulletin》

Effect of a new hypoglycemic agent, A-4166 [(-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine], on postprandial blood glucose excursion: compari...

(-)-N-(trans-4-Isopropylcyclohexanecarbonyl)-D-phenylalanine (A-4166) is a new nonsulfonylurea hypoglycemic agent that lowers blood glucose by stimulating ...

T，Ikenoue，K，... - 《Biological & Pharmaceutical Bulletin》

Recent technologies in pulsatile drug delivery systems

Pulsatile drug delivery systems (PDDS) have attracted attraction because of their multiple benefits over conventional dosage forms. They deliver the drug a...

D Jain，R Raturi，V Jain，... - 《Biomatter》

FORMULATION, CHARACTERIZATION AND IN VITRO EVALUATION OF FLOATING MICROSPHERES OF ESOMEPRAZOLE

The present study involves preparation and evaluation of floating microsphere using Esomeprazole as a model drug for prolongation of the gastric retention ...

BK Sarkar，SS Tanwar，SP Prashant - 《International Journal of Bioassays》

Recent technologies in pulsatile drug delivery systems

Pulsatile drug delivery systems (PDDS) have attracted attraction because of their multiple benefits over conventional dosage forms. They deliver the drug a...

D Jain，R Raturi，V Jain，... - 《Biomatter》

Antidiabetic preparation for oral administration

There is provided a single preparation which directly decreases both of the post prandial blood glucose level and the fasting blood glucose level close to normal levels, by release-sustaining a drug capable of decreasing the post prandia...

C Makino，N Ninomiya，H Orita，... - US

Antidiabetic preparation for oral administration

Preparations comprising a sustained-release drug, which is capable of lowering the after-meal blood sugar level of diabetics to around the normal level, or a mixture of a slow-release drug, which is capable of lowering the after-meal blo...

N Kato，C Makino，N Ninomiya，...

Effect of Decrease in Both Postprandial Blood Glucose (PBG) and Fasting Blood Glucose (FBG) Levels in Normal Beagle Dogs with Nateglinide Enteric Coated Gr...

Nateglinide is a new quick action/short duration (QRSD) type of oral blood glucose regulator, and nateglinide immediate release tablets are used for patien...

C Makino，N Ninomiya，H Sakai，... - 《Chemical & Pharmaceutical Bulletin》

Lyophilized Oral Sustained Release Polymeric Nanoparticles of Nateglinide

The objective of this study is to formulate lyophilized oral sustained release polymeric nanoparticles of nateglinide in order to decrease dosing frequency...

M Kaleemuddin，P Srinivas - 《Aaps Pharmscitech》

Stable colloidal chitosan/alginate nanocomplexes: Fabrication, formulation optimization and repaglinide loading

Objective: The objective of the present work was to optimize the formulation of chitosan/alginate nanocomplexes (CS/ALG NCs) and to evaluate the effect of the amphoteric drug, repaglinide (REP), loading on NCs properties. Methods: CS/ALG...

E Elmowafy，R Osman，EHA El-Shamy，... - 《International Journal of Pharmacy & Pharmaceutical Sciences》