ChemInform Abstract: New Strategy for the Preparation of Nitrogen- and Phosphorus-Containing Chiral Polyfunctional Secondary Alcohols.
摘要:
The use of borane-derived protecting groups for aldehydes containing pyridine and phosphine functionalities allows the performance of highly enantioselective additions of functionalized diorganozincs leading to polyfunctional chiral hydroxy-pyridines and -phosphines with excellent enantioselectivity.
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关键词:
stereochemistry (general, optical resolution) addition reactions protection, deprotection pyridine derivatives quinoline derivatives isoquinoline derivatives organo-phosphorus compounds, acyclic C derivatives
DOI:
10.1002/chin.199849051
年份:
1998
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