摘要：

The reaction of primary nitroalkanes with conjugated enones, in water and in the presence of K 2 CO 3 as base, allows the synthesis of 2-acyl-4-nitrocyclohexanol derivatives in which the diastereoisomer (±)-(1 S ,2 R ,5 R ) is highly predominant. The reaction proceeds by double Michael addition of the nitroalkane to the enone, followed by intramolecular aldol reaction. Previous article in issue Next article in issue

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