ChemInform Abstract: Concise Asymmetric Synthesis of Orthogonally Protected syn- and anti-1,3-Aminoalcohols.
摘要:
The reaction of aldehydes (II) with novel chiral allylation reagent (I) leads to allyl carbonates (III), which are converted into orthogonally protected anti-aminoalcohols (V) by an iridium-catalyzed allylic amidation.
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关键词:
amino alcohols (acyclic compounds) diastereoselective syntheses, enantioselective syntheses (incl. cis/trans-isomerism)
DOI:
10.1002/chin.201326040
年份:
2013
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