摘要：

A compound of formula or a pharmaceutically acceptable salt thereof where -R is hydrogen or methyl; -X- is -CO- or -CH-; -Y- is >CH-A or its vinylogous group >C=CH-CH-A, wherein -A is a -NRR group, where each R and R, equal or different between them, is C-C-alkyl or a phenyl-substituted C-C-alkyl; or -A is the N-radical of a 5- or 6-membered, uncharged (i.e. neither quaternary nor zwitterionic) monocyclic ring, either aromatic or non-aromatic, said ring containing one N atom, two N atoms, three N atoms or an N/O pair of atoms, all other atoms in the ring being carbon, and said ring being optionally mono- or di-substituted by groups selected from C-C-alkyl, benzyl, 2-furanylmethyl and 2-thienylmethyl; -R is hydrogen or a radical C-C-alkyl, C-C-alkoxy, di-(C-C-alkyl)amino, nitro or halogen, said radical being attached at the 2, 3 or 4 substitution positions of the phenyl ring; -R is hydrogen, phenyl, C-C-alkyl, a C-C-alkenyl or alkynyl group with the double or triple bond non-adjacent to the O-C bond, -(CHCHO)-H with = 1, 2 or 3, -(CHOH)-H with = 2, 3 or 4, or -when X is CO-the radical where Y is defined as above.

展开