STRUCTURE AND FUNCTION OF THE PROTEIN TYROSINE PHOSPHATASES [Review]
摘要：
The tyrosine and dual-specificity phosphatases are involved in signaling, cell growth and differentiation, and the cell cycle. The enzymes share a common catalytic mechanism mediated by an active site cysteine, arginine and aspartic acid. Supplementary domains assist in targeting and substrate specificity.
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关键词：
Dual specificity phosphatase Cyclin dependent kinases. Crystal structure Phosphotyrosine Dephosphorylation Transcription. Intermediate Recognition Mechanism Alignment
年份：
1996
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