Indium(III) iodide-mediated Strecker reaction in water: an efficient and environmentally friendly approach for the synthesis of α-aminonitrile via a three-component condensation - ScienceDirect
摘要：
A mild, efficient and environmentally friendly method has been developed for the synthesis of α-aminonitriles via a three-component condensation of aldehyde, amine and TMSCN in the presence of a catalytic amount of indium(III) iodide in water. The reactions proceeded smoothly at room temperature in water to generate the corresponding products in moderate to excellent yields.
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关键词：
Strecker reaction alpha-aminonitrile indium(III) iodide water three-component reaction ONE-POT SYNTHESIS LEWIS-ACID CATALYST TRIFLUOROMETHYLATED HOMOALLYLIC ALCOHOLS HIGHLY STEREOSELECTIVE-SYNTHESIS UNACTIVATED ALKYL-HALIDES SOLVENT-FREE CONDITIONS AQUEOUS-MEDIA ORGANIC-REACTIONS FACILE SYNTHESIS BOND FORMATIONS
年份：
2008
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