Enantio- and diastereoselective hydrogenation via dynamic kinetic resolution by a cationic iridium complex in the synthesis of beta-hydroxy-alpha-amino acid esters
摘要:
Anti-selective asymmetric hydrogenation of alpha-amino-beta-keto esters via dynamic kinetic resolution under low hydrogen pressure has been achieved by an easily-handled cationic iridium complex with tetrakis[3,5-bis(trifluoromethyl)phenyl] borate (BARF) as a counterion.
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关键词:
STEREOSELECTIVE ASYMMETRIC HYDROGENATION CHIRAL METAL-COMPLEXES SIDE-CHAIN SEGMENT CATALYZED HYDROGENATION EFFICIENT SYNTHESIS METHOXYTYROSINE POLYOXYPEPTINS PHTHALIMIDE PAPUAMIDES OLEFINS
DOI:
10.1021/ol061796v
年份:
2006
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