Enantio- and diastereoselective hydrogenation via dynamic kinetic resolution by a cationic iridium complex in the synthesis of beta-hydroxy-alpha-amino acid esters

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24

作者:

Makino, KIwasaki, MHamada, Y

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摘要:

Anti-selective asymmetric hydrogenation of alpha-amino-beta-keto esters via dynamic kinetic resolution under low hydrogen pressure has been achieved by an easily-handled cationic iridium complex with tetrakis[3,5-bis(trifluoromethyl)phenyl] borate (BARF) as a counterion.

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DOI:

10.1021/ol061796v

年份:

2006

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