摘要：

Explores the potential of alpha-halogenated acetophenones as a novel class of potent, covalent protein tyrosine phosphatases (PTP) inhibitors. Phosphorylation of proteins on tyrosine residues; Protein tyrosine kinases; Catalysis of the formation of phosphotyrosine in proteins; Determination of the dissociation constant of the noncovalent complex.

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