KINASE INHIBITORS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE
申请(专利)号：
CA20082695857
申请日期：
2008-08-08
公开/公告号：
CA2695857C
公开/公告日期：
2015-08-04
申请(专利权)人：
LEXICON PHARMACEUTICALS, INC.
摘要：
Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions com .pi.sin them and methods of their use, X is O or NR A; Y is O, NR R, or C(R R)2; A is cycloalkyl, aryl or heterocycle; R A is hydrogen, cyano, nitro, R A1, SO2R A1, SO2NR A1, or SO2N(R A1)2;
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