USING IL-1 ANTAGONISTS FOR TREATING GOUT
申请(专利)号:
RU20090118962
申请日期:
2007-10-19
公开/公告号:
RU2450824C2
公开/公告日期:
2012-05-20
申请(专利权)人:
RIDZHENERON FARMAS'JUTIKALZ, INK.
摘要:
FIELD: medicine, pharmaceutics.;SUBSTANCE: group of inventions refers to medicine and concerns using IL-1 antagonists for treating gout. Substance of the invention involves using an interleukin 1 (IL-1) antagonist representing a fused protein containing an IL-1 binding part of the outer human domain IL-1RAcP, an IL-1 binding part of the outer human domain IL-1R1 and a multimerisation component, for treating gout. Preferentially, the IL-1 antagonist is protein SEQ ID NO: 10 (Rinolacept).;EFFECT: creation of the product which allows less frequent introduction to reduce symptoms of gout and recurrent attacks, and decrease side effects associated with common methods of treating.;11 cl, 2 ex, 1 tbl
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