Modified mucoadhesive polymers for the peroral administration of mainly elastase degradable therapeutic (poly)peptides

A number of elastatinal–polymer conjugates, having the inhibitor linked to sodium carboxymethyl cellulose (Na-CMC), poly(acrylic acid) (PAA) and poly(acry...

A Bernkop-Schnürch，GH Schwarz，M Kratzel - 《Journal of Controlled Release》

PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION

Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat d...

G Klaerner，EF Connor，RK Gbur，...

Oral administration of iron-saturated bovine lactoferrin-loaded ceramic nanocapsules for breast cancer therapy and influence on iron and calcium metabolism.

We determined the anticancer efficacy and internalization mechanism of our polymeric–ceramic nanoparticle system (calcium phosphate nanocores, enclosed in...

K Jagat，M Ganesh，K Rupinder，... - 《International Journal of Nanomedicine》

Starch granules as a vehicle for the oral administration of immobilized antigens

Microparticles of diverse compositions are often used as carriers for interesting antigens. In this work, we propose the use of natural microparticulated s...

D Guillén，S Moreno-Mendieta，R Pérez，... - 《Carbohydrate Polymers》

Enteric Coating Systems for the Oral Administration of Bioactive Calcium Phosphate Nanoparticles Carrying Nucleic Acids into the Colon

A system to deliver bioactive calcium phosphate nanoparticles (about 60 nm, loaded with nucleic acids) across the stomach into the colon was developed by f...

S Hosseini，K Wey，M Epple - 《Chemistryselect》

A novel iron-conjugated acid-modified chitosan derivatives as an oral phosphate binding agent to improve phosphorus adsorption efficacy in vitro and in viv...

Current phosphate binders used for hyperphosphatemia treatment need large daily dose which make patients' compliance worse and the therapeutic efficacy may...

JLSA Lin - 《Carbohydrate Polymers Scientific & Technological Aspects of Industrially Important Polysaccharides》

Starch granules as a vehicle for the oral administration of immobilized antigens

Microparticles of diverse compositions are often u

Ricardo，Perez，Silvia，... - 《Carbohydrate Polymers Scientific & Technological Aspects of Industrially Important Polysaccharides》