An emerging approach for diagnosing LC relies on volatile organic compounds (VOC), viz. organic compounds with relatively high vapor pressure or volatility, that can be detected in the headspace of cancer cells or blood samples, and/or i...
Here we review and illustrate the rich diversity of compounds observed in exhaled breath with a particular focus on lung cancer patients. Each of the ...
Hakim M., Broza Y. Y., Barash O., et al. Volatile organic compounds of lung cancer and possible biochemical pathways. Chemical Reviews . 2012; 112 (11):5949–5966. doi: 10.1021/cr300174a. [ Cross Ref ]...
Lung cancer is the most common cause of cancer deaths, its global incidence is rising, and continuing rises are predicted. The potential to diagnose lung c...
According to the World Health Organization (WHO), 1.37 million people died of lung cancer all around the world in 2008, occupying the first place in all cancer-related deaths. However, this number might be decreased if patients were dete...
Volatile organic compounds of lung cancer and possible biochemical pathways. Chem Rev. 2012;112:5949鈥 66. Stitzel S, Arnecke M, Walt D. Artificial noses. Ann Rev Biomed Eng. 2011;13:1鈥 25. References Disclosure of Interest None...
Volatile organic compounds of lung cancer and possible biochemical pathways. Chem Rev. 2012;112:5949鈥 66. Stitzel S, Arnecke M, Walt D. Artificial noses. Ann Rev Biomed Eng. 2011;13:1鈥 25. Disclosure of Interest None declared...
Vegetation provides a major source of reactive carbon entering the atmosphere. These compounds play an important role in (1) shaping global tropospheric ch...
PURPOSE: Circulating cell-free DNA is present in increased amounts in the blood of cancer patients, but the clinical relevance of this phenomenon remains u...
Tumour growth is accompanied by gene and/or protein changes that may lead to peroxidation of the cell membrane species and, hence, to the emission of volat...
Background Lung cancer is one of the leading causes of death in Europe and the western world. At present, diagnosis of lung cancer very often happens late ...
There is experimental evidence that volatile substances in human breath can reflect presence of neoplasma. Volatile aldehydes were determined in exhaled br...
A combination of biomarkers in a multivariate model may predict disease with greater accuracy than a single biomarker employed alone. We developed a non-li...
The past decade has seen a revival of interest in the metabolic adaptations of tumours, named for their original discoverer, Otto Warburg. Warburg reported...
We propose a nanomedical device for the classification of lung cancer (LC) histology. The device profiles volatile organic compounds (VOCs) in the headspac...
We have investigated the generation of prooxidant state shortly after administration of N-nitrosamines (NA) to rats. N-Nitrosodimethylamine (NDMA) was found to increase ethane exhalation (EE) rapidly in a dose-related manner. EE remained...
To be, or not to be?" This question is not only Hamlet's agony but also the dilemma of mitochondria in a cancer cell. Cancer cells have a high glycolysis r...
The cytochrome P-450-dependent metabolism of n -pentane was studied by head-space gas chromatographic analysis of incubations with liver microsomes and re...
