摘要：

Novel N-aryltriazole nucleosides were synthesized via a Cu-mediated CN cross-coupling reaction, using 3-aminotriazole acyclonucleosides and various boronic acid reagents. Interestingly, N-arylation proceeded much more rapidly on the amide group than on the amine group, leading to selective N-arylation of the amide functionality on nucleosides containing both groups on the triazole nucleobase.

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