摘要：

NEW MATERIAL:A compound expressed by formula I [R<1> is substituted phenyl or ferrocenyl expressed by formula II (both R<2> and R<3> are OH or at least either one of R<2> and R<3> is phenoxy)]. USE:An antimicrobial agent, tyrosine kinase inhibitor, having possibility of being useful as a carcinostatic agent and carcinogenic inhibitor and useful as a synthetic intermediate for many organic compounds. PREPARATION:An aldehyde expressed by the formula R<1>-CHO and alpha- cyanoacetamide are subjected to the Knoevenagel reaction using a basic catalyst, e.g. piperidine or ammonium acetate, to afford the aimed compound expressed by formula I. Alternatively, the aldehyde expressed by the formula R<1>-CHO is condensed with the alpha-cyanoacetamide on the absence or presence of an acid or base catalyst, e.g. sulfuric acid or pyridine, to give the aimed compound expressed by formula I.

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