METHOD OF MANUFACTURING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER[KR20000055108A]

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8

申请(专利)号:

INPCT/2001/00591/DEL

申请日期:

2001-07-04

公开/公告号:

IN2001DN00591A

公开/公告日期:

2008-06-20

发明人:

YU HO SUNGII KIM KYUNGLW JongRK RokII HWANG DAE

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摘要:

The present invention relates to a process for preparing (R)-4-cyano-3-hydroxybutyric acid ester derivatives and more particularly, to a process for preparing optically pure (R)-4-cyano-3-hydroxybutyric acid ester derivatives expressed by formula (1) in high yield by performing cyanation and sequential esterification of (S)-3,4-epoxybutyric acid salt as a starting material. In said formula, R represents linear or branched alkyl group with 1~5 carbon atoms or benzyl group.

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