Enantioselective Organocatalytic Three-Component Vinylogous Michael/Aldol Tandem Reaction among 3-Alkylidene oxindoles, Methyleneindolinones, and Aldehydes
摘要：
We reported a one-pot enantioselective three-component vinylogous Michael/aldol tandem reaction of prochiral 3-alkylidene oxindoles with methyleneindolinones and aldehydes using bifunctional organocatalysts. A variety of enantioenriched 3,3-disubstituted oxindoles
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关键词：
DIELS-ALDER QUATERNARY STEREOCENTERS ASYMMETRIC-SYNTHESIS 3-ALKENYL-2-SILYLOXYINDOLES HYDROXYMETHYLATION SPIROOXINDOLES TRIENAMINES DIASTEREO ACCESS
DOI：
10.1021/acs.joc.1c02180
年份：
2022
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