Compositions and methods of developing oligonucleotides and oligonucleotide analogs having antiviral activity
申请(专利)号:
AU19970011241
申请日期:
1996-11-27
公开/公告号:
AU1124197A
公开/公告日期:
1997-06-19
申请(专利权)人:
PENN STATE RESEARCH FOUNDATION; THE
摘要:
Methods of identifying and preparing anti-infectious agent compounds comprising the steps of incubating single stranded nucleic acids or nucleic acid analogs in the presence of infectious agents, selecting for nucleic acids or nucleic acid analogs which bind infectious agents, amplifying selected nucleic acids or nucleic acid analogs, repeating the selection steps and assaying for anti-infection activity are disclosed. Compositions that have anti-infectious activity against Rous sarcoma virus are also disclosed. Methods of identifying anti-tumor agent compounds are also disclosed.
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