Syntheses of Triazole-Modified Zanamivir Analogues via Click Chemistry and anti-AIV Activities
摘要：
Treatment of methyl 5-acetamido-2,4,7,8,9-penta-O-acetyl-3,5-dideoxy-β-l-glycero-d-galacto-2-nonulopyranosidonate (1) with cyclic secondary amines in pyridine at room temperature for 24h afforded unusual products (2a–g). Related experiments were carried out to explain the formation of 4-amination and 2-O-deacetylation of peracetylated sialic acid derivatives (2a–g). This reaction may provide a...
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DOI：
10.1016/j.bmcl.2006.07.047
年份：
2006
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来源期刊
Bioorganic & Medicinal Chemistry Letters
2006/11/01
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