摘要：

Cerebral ischemic stoke is a disease in which oxidative stress, activation of inflammatory storms, interference, induction of apoptosis, and blood reperfusion aggravate the tissue and cell damage due to ischemia and hypoxia. Mesenchymal stem cells (MSCs) induce the angiogenesis and can be used to treat the ischemiareperfusion injury, anti-apoptosis and anti-inflammatory. Preclinical studies have confirmed that targeted delivery of mesenchymal-derived exosomes to recipient cells exerts the effects of inducing angiogenesis, anti-apoptosis, and anti-inflammatory, while avoiding the shortcomings of mesenchymal stem cell therapy. The purpose of this study is to summarize the mechanism of exosomes derived from mesenchymal stem cells in the treatment of stroke so as to provide new opportunities for treating ischemic cerebrovascular disease clinically.

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