An insight review on the neuropharmacological effects, mechanisms of action, pharmacokinetics and toxicity of mitragynine
摘要:
Mitragynine is a primary psychoactive alkaloid inMitragyna speciosa(kratom).Mitragynine exhibits opium-like effects by interacting with opioid receptors.Mitragynine interacts with adrenergic and serotonergic receptorsin the central nervous system.Mitragynine shows antinociceptive, anti-inflammatory, sedative, stimulant, anti-depressant, and anxiolytic effects.
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DOI:
10.1016/j.biopha.2024.116134
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