The period clock gene is expressed in central nervous system neurons which also produce a neuropeptide that reveals the projections of circadian pacemaker cells within the brain of Drosophila melanogaster.
摘要：
The period protein (PER) is an essential component of the circadian clock in Drosophila melanogaster. Although PER-containing pacemaker cells have been previously identified in the brain, the neuronal network that comprises the circadian clock remained unknown. Here it is shown that some PER neurons are also immunostained with an antiserum against the crustacean pigment-dispersing hormone (PDH). This antiserum reveals the entire arborization pattern of these pacemaker cells. The arborizations of these neurons are appropriate for modulation of the activity of many neurons and they might interact with PER-containing glial cells. A putative physiological role of PDH in the circadian system is discussed.
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关键词：
Brain Chronobiology Drosophila melanogaster Genes Insect Nuclear Proteins 脑 时间生物学 果蝇 黑腹 基因 昆虫 核蛋白质类
DOI：
10.1073/pnas.92.2.612
被引量：
年份：
1995
国家科技图书文献中心
(权威机构)
Semantic Scholar
万方医学
掌桥科研
dx.doi.org
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