Significant overexpression of urokinase‐type plasminogen activator in pancreatic adenocarcinoma using real‐time quantitative reverse transcription polymerase chain reaction
摘要：
Background and Aims: Overexpression of urokinase-type plasminogen activator (uPA) has been shown to be strongly associated with an increased metastatic potential and poor prognosis in a variety of human malignancies. It was hypothesized that uPA would be overexpressed in highly metastatic pancreatic cancer. The aims of this study were to analyze uPA mRNA expression in pancreatic cancer and to correlate this to the expression of uPA protein and to the stage of the disease.
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关键词：
pancreatic cancer real‐time quantitative reverse transcription polymerase chain reaction urokinase‐type plasminogen activator
DOI：
10.1111/j.1440-1746.2004.03531.x
被引量：
年份：
2005
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