Diaryl ether inhibitors of farnesyl-protein transferase
摘要：
Imidazolemethyl diaryl ethers are potent inhibitors of farnesyl-protein transferase. The SNAr displacement reaction used to prepare these diaryl ethers was amenable to rapid parallel synthesis of FPTase inhibitors. The use of a broad range of commercially available phenols quickly identified compounds which proved active in cells.
展开
关键词：
Magnolia grandiflora Magnoliaceae sesquiterpenoids 6 alpha,11-dihydroxy-12,13-diacetoxylem-1,3-diene 4 alpha,6 alpha,10 alpha-trihydroxy-13-acetoxyguaia-11-ene 12,13-diacetoxyguaia-4 alpha,6 alpha,10 alpha,11-tetraol
DOI：
10.1016/S0960-894X(01)00162-7
被引量：
年份：
2001
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
