5- 1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl! salicylamide and physiologically acceptable acid addition salts thereof
申请(专利)号:
US05/420547
申请日期:
19731130
公开/公告号:
US04012444A
公开/公告日期:
19770315
申请(专利权)人:
ALLEN & HANBURYS LIMITED
被引量:
摘要:
Compounds of the formula: ##STR1## and physiologically acceptable acid addition salts thereof, in which R.sup.1 is< P>A. AN ARYLALKYL GROUP, THE ALKYL PORTION OF WHICH CONTAINS FROM 1 TO 6 CARBON ATOMS AND THE ARYL PORTION OF WHICH MAY BE SUBSTITUTED BY ONE OR MORE ALKOXY GROUPS OR HYDROXY GROUPS; ORB. AN ARYLOXYALKYL GROUP, THE ALKYL PORTION OF WHICH CONTAINS FROM 1 TO 6 CARBON ATOMS, AND THE ARYLOXY PORTION OF WHICH IS SUBSTITUTED WITH ONE OR MORE ALKOXY OR HYDROXY GROUPS.These compounds have a blocking action on both &agr;- and &bgr;-adrenergic receptors. Processes for the production of these compounds and pharmaceutical compositions containing them are also provided.
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