Multiple, Distinct Forms of Bovine and Human Protein Kinase C Suggest Diversity in Cellular Signaling Pathways
摘要：
A new family of protein kinase C-related genes has been identified in bovine, human, and rat genomes. The alpha-, beta-, and gamma-type protein kinase sequences are highly homologous, include a kinase domain, and potential calcium-binding sites, and they contain interspersed variable regions. The corresponding genes are located on distinct human chromosomes; the possibility of even greater genetic complexity of this gene family is suggested by Northern and Southern hybridization analyses.
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关键词：
Animals Base Sequence Cattle Chromosome Mapping Chromosomes, Human, 16-18 DNA Genes Humans Nucleic Acid Hybridization Protein Kinase C
DOI：
10.1126/science.3755548
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年份：
1986
Taylor & Francis
万方医学
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