Population-based study of autoimmune conditions and the risk of specific lymphoid malignancies
摘要:
Some autoimmune conditions are associated with increased risk of lymphoid malignancies, but information on specific malignancy subtypes is limited. From the U.S. Surveillance Epidemiology and End Results-Medicare database, we selected 44,350 lymphoid malignancy cases (≥67 years) and 122,531 population-based controls. Logistic regression was used to derive odds ratios (ORs) comparing the prevalence of autoimmune conditions in cases and controls, by lymphoid malignancy subtype, adjusted for gender, age at malignancy/selection, year of malignancy/selection, race and number of physician claims. The strongest associations observed by non-Hodgkin lymphoma (NHL) subtypes were diffuse large B-cell lymphoma with rheumatoid arthritis (OR 1.4, 95%CI 1.2–1.5) and Sjögren syndrome (2.0, 1.5–2.8); T-cell lymphoma with hemolytic anemia (9.7, 4.3–22), psoriasis (3.1, 2.5–4.0), discoid lupus erythematosus (4.4, 2.3–8.4) and celiac disease (5.0, 2.4–14.); and
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DOI:
10.1002/ijc.24287
被引量:
年份:
2009
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