Convenient synthesis of optically active 2 H -azirine-2-carboxylic esters by Swern oxidation of aziridine-2-carboxylic esters
摘要:
The synthesis of optically active 2 H -azirine-2-carboxylic esters was achieved by Swern oxidation of the corresponding aziridine-carboxylic esters. For both trans and cis aziridine esters this oxidation gives a regioselective introduction of the double bond which is not in conjugation with the ester function. The methyl ester of ent -Azirinomycin was prepared in this manner.
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DOI:
10.1002/chin.199540126
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年份:
1995
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来源期刊
Tetrahedron Letters
26 June 1995
引用走势
2010
被引量:67
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