Association of class I major histocompatibility heavy and light chainsinduced by viral peptides

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阅读量:

54

摘要:

We describe a cell in which association of a major histocompatibility complex class I heavy chain with β 2 -microglobulin is induced by a peptide derived from influenza nucleoprotein. Association of anti-genie peptides with the binding site of class I molecules may be required for correct folding of the heavy chain, association with β 2 -microglobulin and transport of the antigen-MHC complex to the cell surface.

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DOI:

10.1038/340443a0

被引量:

2007

年份:

1989

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