摘要：

Isopinocampheylborane, IpcBH2 (2), achieves asymmetric hydroboration of trans-disubstituted alkenes with exceptionally high asymmetric induction. The product alcohols, obtained after oxidation of the intermediate organoboranes, exhibit enantiomeric purities in the range of 70-92% ee. The enantiomeric purities of the products increase with the increasing steric requirement of the alkyl substituent in the trans-disubstituted alkene.

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