Synthesis of L-2-(2,3-dicarboxyclopropyl)glycines. Novel conformationally restricted glutamate analogues
摘要:
New conformationally restricted glutamate agonists 1 and 2 possessing both an extended and a folded conformation of L-glumatamate in their structures have been efficiently synthesized in a stereoselective manner. The synthesis of 1 involved a novel α-carbomethoxycyclopropyl anion equilibration.
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DOI:
10.1016/S0960-894X(00)80083-9
被引量:
年份:
1993
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