A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells.

阅读量:

49

作者:

GiannakakouParaskeviGussioRick

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摘要:

Presents information on a study which identified tubulin residues important for epothilone binding. Investigation of the conformational behavior of epothilone; Qualities of epothilone; Materials and methods of the study; Results and discussion.

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被引量:

765

年份:

2000

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