Enhanced survival of retinal ganglion cells is mediated by Müller glial cell-derived PEDF
摘要：
•Loss of viable retinal ganglion cells (RGC) in hypoxia is due to apoptosis.•RGC survival is increased by co-culture with Müller glial cells (MGC).•Pigment-epithelium derived factor (PEDF) released from MGC acts neuroprotective.•PEDF exposure leads to activation of nuclear factor (NF)-κB in RGC.•Neutralizing NF-κB activity reduces RGC survival.
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DOI：
10.1016/j.exer.2014.08.004
被引量：
年份：
2014
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