The mesengenic process.
摘要：
The genesis of mesodermal tissues, such as bone, cartilage, muscle, marrow stoma, tendon, fat, dermis, and connective tissues, in either embryos or adult organisms is referred to as the mesengenic process. The process is involved in the continual rejuvenation of each mesenchymal tissue and provides a logic for understanding the rapid repair of tissue injuries. The isolation and identification of mesenchymal stem cells and their quantity and distribution allow a better understanding of the turnover and repair motifs used in adult organisms. Mesenchymal stem cells undergo proliferative and commitment events, and their progeny enter discrete lineages that result in the ultimate terminal differentiation of definitive phenotypes such as osteoblasts, chondrocytes, or myoblasts. The molecular and cellular control of the mesengenic process provides a logic for designing cell therapies for the reconstruction of mesenchymal tissues.
展开
关键词：
Humans Cartilage Ligaments Muscles Bone and Bones Bone Marrow Cells Stem Cell Transplantation Cell Division Adolescent Adult
DOI：
10.1016/S0094-1298(20)31020-8
被引量：
年份：
1994
相似文献
参考文献
引证文献
来源期刊
引用走势
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
