Recent Developments in the Catalytic Asymmetric Cyanation of Ketimines
摘要:
Contrasting styles: The two catalysts shown are both effective for the cyanation of ketimines. The metal-based catalyst 1, developed by a standard approach, displays a very broad scope and substrate generality. The metal-free catalyst 2 was designed by a combination of random screening and mechanism-based optimization.
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DOI:
10.1002/anie.200301686
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年份:
2004
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来源期刊
Angewandte Chemie International Edition
2004年03月26日
引用走势
2007
被引量:79
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