Vitamin D3 supplementation using an oral spray solution resolves deficiency but has no effect on VO2 max in Gaelic footballers: results from a randomised, double-blind, placebo-controlled trial

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作者：

JJ Todd，McSorley, Emeir M.，LK Pourshahidi，SM Madigan，E Laird，M Healy，PJ Magee

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摘要：

PURPOSE: Vitamin D inadequacy is a global health concern in athletes as well as the general population. Whilst the role of vitamin D in skeletal health is well defined, there remains uncertainty over whether vitamin D supplementation has an added benefit beyond bone health. METHODS: This randomised placebo-controlled trial in healthy male and female Gaelic footballers (n=42) investigated the effect of vitamin D 3 supplementation [3000IU (75g) daily for 12weeks, via an oral spray solution] on VO 2 max which was the primary outcome measure. Secondary outcomes included skeletal muscle and lung function. RESULTS: Supplementation significantly increased total 25-hydroxyvitamin D concentrations compared to the placebo group (mean±SD change from baseline, 36.31±32.34 vs. 6.11±23.93nmol/L, respectively; P=0.006). At baseline, 50 and 22% of footballers presented with vitamin D insufficiency (31-49nmol/L) and deficiency (<30nmol/L), respectively. Total 25-hydroxyvitamin D concentration did not significantly correlate with any measure of physical performance. Analysis of covariance (ANCOVA) models demonstrated that vitamin D supplementation over 12weeks had no significant effect on VO 2 max (P=0.375), vertical jump height (P=0.797), left and right handgrip strength (P=0.146 and P=0.266, respectively), forced vital capacity (P=0.573) or forced expiratory volume at 1s (P=0.665), after adjusting for confounders. The high prevalence of vitamin D inadequacy observed in this cohort of collegiate Gaelic footballers supports the need for vitamin D supplementation during wintertime to avoid being at risk of poor bone health. CONCLUSIONS: Twelve-week daily supplementation with 3000IU (75g) vitamin D 3 successfully resolved deficiency but did not have any significant effect on VO 2 max, skeletal muscle or lung function.

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关键词：

Vitamin D VO2 max Athletes Randomised controlled trial Football

DOI：

10.1007/s00394-016-1202-4

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年份：

2017